Bio-Dome is a 1996 American film directed by Jason Bloom. Bio-Dome was produced by Motion Picture Corporation of America on a budget of $10 million and was distributed theatrically by Metro-Goldwyn-Mayer.
The plot of the film revolves around two clumsy, dim-witted slackers who, while on a road trip, look for a toilet stop in what they believe is a shopping mall, which in fact turns out to be a "bio-dome", a form of a closed ecological system in which five scientists are to be hermetically sealed for a year. The film has themes of environmentalism, combined with substance abuse, sexual innuendo, and toilet humor.
The film stars Stephen Baldwin and Pauly Shore, and has cameo appearances by celebrities such as Roger Clinton, Kylie Minogue, Patricia Hearst, and Rose McGowan. Jack Black and Kyle Gass first came to global attention in Bio-Dome in which they performed together as Tenacious D on-screen for the first time.
The film grossed $26,000,000 at the box office in North America. Bio-Dome was widely panned by mainstream critics at the time. The film, however, has continued to play on television, and is embraced by many fans as a classic "goofball" comedy.