D.O.A. is a film noir drama film directed by Rudolph Mate, considered a classic of the genre. The frantically paced plot revolves around a doomed man's quest to find out who has poisoned him and why. This film marks the debuts of Beverly Garland (as Beverly Campbell) and Laurette Luez. The film stars Edmond O'Brien and Pamela Britton.
Leo C. Popkin produced D.O.A. for his short-lived Cardinal Pictures. Due to a filing error the copyright to the film was not renewed on time, causing it to fall into the public domain.
In 2004, D.O.A. was selected for preservation in the United States National Film Registry by the Library of Congress as being "culturally, historically, or aesthetically significant."